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Magic™ Membrane Protein Human IL10RB (Interleukin 10 receptor subunit beta) Expressed in NS0 for Antibody Discovery, Partial (20-220aa) (CAT#: MPX0753K)

Datasheet
This product is a 51 kDa Human IL10RB membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL10RB
  • Protein Length
  • Partial (20-220aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 51 kDa
  • TMD
  • 1
  • Sequence
  • MVPPPENVRMNSVNFKNILQWESPAFAKGNL
    TFTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDW
    VNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYN
    SWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNK
    AGEWSEPVCEQTTHDETVPS

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL10RB
  • Full Name
  • Interleukin 10 receptor subunit beta
  • Introduction
  • The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
  • Alternative Names
  • IL10RB; CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10RB; cytokine receptor class-II CRF2-4; cytokine receptor class-II member 4; cytokine receptor family 2 member 4; cytokine receptor family II, member 4; interleukin 10 receptor, beta; interleukin-10 receptor subunit 2; Interleukin 10 receptor subunit beta

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