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Magic™ Membrane Protein Human IL1RAP (Interleukin 1 receptor accessory protein) Expressed in HEK293 for Antibody Discovery, Partial (21-359aa) (CAT#: MPX0732K)

Datasheet
This product is a 40 kDa Human IL1RAP membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL1RAP
  • Protein Length
  • Partial (21-359aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 40 kDa
  • TMD
  • 1
  • Sequence
  • SERCDDWGLDTMRQIQVFEDEPARIKCPLF
    EHFLKFNYSTAHSAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLW
    FRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSPMKLPVHKLY
    IEYGIQRITCPNVDGYFPSSVKPTITWYMGCYKIQNFNNVIPEGMNLSFL
    IALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNAVPPVIHSPND
    HVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDVTINE
    SISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQK
    VPAPRYTVE

Product Description

  • Activity
  • Yes
  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL1RAP
  • Full Name
  • Interleukin 1 receptor accessory protein
  • Introduction
  • This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
  • Alternative Names
  • IL1RAP; IL1R3; C3orf13; IL-1RAcP; IL-1 receptor accessory protein; interleukin-1 receptor 3; interleukin-1 receptor accessory protein beta; Interleukin 1 receptor accessory protein

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