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Magic™ Membrane Protein Human IL27RA (Interleukin 27 receptor subunit alpha) Expressed in NS0 for Antibody Discovery, Partial (34-516aa) (CAT#: MPX0302K)

Datasheet
This product is a 79 kDa Human IL27RA membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL27RA
  • Protein Length
  • Partial (34-516aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 79 kDa
  • TMD
  • 1
  • Sequence
  • GSAGPLQCYGVGPLGDL
    NCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMS
    DKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVH
    WAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELAT
    GYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEE
    PLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSA
    VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLE
    HVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASG
    LASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLT
    HYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPP
    GPILRLHLPDNTLRWK

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL27RA
  • Full Name
  • Interleukin 27 receptor subunit alpha
  • Introduction
  • In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
  • Alternative Names
  • IL27RA; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; T-cell cytokine receptor type 1; class I; cytokine receptor; cytokine receptor WSX-1; cytokine receptor-like 1; interleukin 27 receptor, alpha; type I T-cell cytokine receptor; Interleukin 27 receptor subunit alpha

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