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Magic™ Membrane Protein Human ITGA6 (Integrin subunit alpha 6) Full Length (CAT#: MPC1877K) Made to Order

This product is a 126.6 kDa Human ITGA6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ITGA6
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 126.6 kDa
  • TMD
  • 1
  • Sequence
  • MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAM
    HWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFD
    NDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDI
    FGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDF
    HYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLV
    PVPANSYLGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFS
    LDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEG
    LASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRW
    NNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYH
    GSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTI
    FRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAG
    YNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKV
    CMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDE
    PKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGV
    PELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS
    AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVT
    FDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFG
    GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISN
    GKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDD
    NRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTF
    LEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYS
    GVPWWIILVAILAGILMLALLVFILWKCGFFKRSRYDDSVPRYHAVRIRK
    EEREIKDEKYIDNLEKKQWITKWNENESYS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ITGA6
  • Full Name
  • Integrin subunit alpha 6
  • Introduction
  • The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ITGA6; CD49f; VLA-6; ITGA6B; integrin alpha-6; CD49 antigen-like family member F; integrin alpha6B; integrin, alpha 6; Integrin subunit alpha 6

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