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Magic™ Membrane Protein Human KCNJ8 (Potassium inwardly rectifying channel subfamily J member 8) Full Length (CAT#: MPC0614K) Made to Order

Datasheet
This product is a 47.9 kDa Human KCNJ8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNJ8
  • Protein Length
  • Full length
  • Protein Class
  • Transporterer; Ion channel
  • Molecular Weight
  • 47.9 kDa
  • TMD
  • 2
  • Sequence
  • MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNI
    REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGD
    IYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE
    ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIA
    VRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPV
    DNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
    ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAA
    PRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRR
    NNSSLMVPKVQFMTPEGNQNTSES

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNJ8
  • Full Name
  • Potassium inwardly rectifying channel subfamily J member 8
  • Introduction
  • Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS).
  • Alternative Names
  • KIR6.1; uKATP-1; ATP-sensitive inward rectifier potassium channel 8; inward rectifier K(+) channel Kir6.1; inwardly rectifying potassium channel KIR6.1; potassium channel, inwardly rectifying subfamily J member 8; potassium voltage-gated channel subfamily J member 8; KCNJ8; Potassium inwardly rectifying channel subfamily J member 8

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