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Magic™ Membrane Protein Human KCNMA1 (Potassium calcium-activated channel subfamily M alpha 1) Full Length (CAT#: MPC0631K) Made to Order

Datasheet
This product is a 137.5 kDa Human KCNMA1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNMA1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 137.5 kDa
  • TMD
  • 7
  • Sequence
  • MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSS
    SSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFG
    GLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEE
    AVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS
    NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVV
    DFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKL
    VNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTM
    STVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGS
    YSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNL
    ELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDA
    EDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAIC
    LAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNE
    MYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGN
    HLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKM
    SIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCS
    TSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQID
    NMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDV
    SSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVS
    ILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNI
    KSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP
    IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSAT
    YFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRV
    AQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQ
    CTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSS
    KKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • 1D4 tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNMA1
  • Full Name
  • Potassium calcium-activated channel subfamily M alpha 1
  • Introduction
  • MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • SLO; BKTM; SLO1; hSlo; IEG16; LIWAS; MaxiK; PNKD3; SAKCA; mSLO1; CADEDS; KCa1.1; SLO-ALPHA; bA205K10.1; calcium-activated potassium channel subunit alpha-1; uncharacterized protein LOC3778; BK channel alpha subunit; BKCA alpha subunit; big potassium channel alpha subunit; calcium-activated potassium channel, subfamily M subunit alpha-1; k(VCA)alpha; maxi-K channel HSLO; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; slo homolog; slowpoke homolog; stretch-activated Kca channel; KCNMA1; Potassium calcium-activated channel subfamily M alpha 1

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