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Magic™ Membrane Protein Human LAT (Linker for activation of T cells) Full Length (CAT#: MPC2097K) Made to Order

This product is a 27.9 kDa Human LAT membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LAT
  • Protein Length
  • Full length
  • Protein Class
  • Immunity
  • Molecular Weight
  • 27.9 kDa
  • TMD
  • 1
  • Sequence
  • MEEAILVPCVLGLLLLPILAMLMALCVHCHRLPGSYDSTSSDSLYPRGIQ
    FKRPHTVAPWPPAYPPVTSYPPLSQPDLLPIPRSPQPLGGSHRTPSSRRD
    SDGANSVASYENEGASGIRGAQAGWGVWGPSWTRLTPVSLPPEPACEDAD
    EDEDDYHNPGYLVVLPDSTPATSTAAPSAPALSTPGIRDSAFSMESIDDY
    VNVPESGESAEASLDGSREYVNVSQELHPGAAKTEPAALSSQEAEEVEEE
    GAPDYENLQELN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • LAT
  • Full Name
  • Linker for activation of T cells
  • Introduction
  • The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • LAT; LAT1; pp36; IMD52; linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; linker for activation of T cells, transmembrane adaptor; p36-38; Linker for activation of T cells

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