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Magic™ Membrane Protein Human LMBR1 (Limb development membrane protein 1) Full Length (CAT#: MPC2562K) Made to Order

Datasheet
This product is a made-to-order Human LMBR1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LMBR1
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 9
  • Sequence
  • MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQE
    DEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLSFPQNYYIQWL
    NGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKGIRARILET
    LVMLLLLALLILGIVWVASALIDNDAASMESLYDLWEFYLPYLYSCISLM
    GCLLLLLCTPVGLSRMFTVMGQLLVKPTILEDLDEQIYIITLEEEALQRR
    LNGLSSSVEYNIMELEQELENVKTLKTKLERRKKASAWERNLVYPAVMVL
    LLIETSISVLLVACNILCLLVDETAMPKGTRGPGIGNASLSTFGFVGAAL
    EIILIFYLMVSSVVGFYSLRFFGNFTPKKDDTTMTKIIGNCVSILVLSSA
    LPVMSRTLGITRFDLLGDFGRFNWLGNFYIVLSYNLLFAIVTTLCLVRKF
    TSAVREELFKALGLHKLHLPNTSRDSETAKPSVNGHQKAL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • LMBR1
  • Full Name
  • Limb development membrane protein 1
  • Introduction
  • This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
  • Alternative Names
  • LMBR1; LSS; TPT; ZRS; ACHP; PPD2; THYP; DIF14; C7orf2; limb region 1 protein homolog; differentiation-related gene 14 protein; limb region 1 homolog; Limb development membrane protein 1

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