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Magic™ Membrane Protein Human LRRC8A (Leucine rich repeat containing 8 VRAC subunit A) Full Length (CAT#: MPC0657K) Made to Order

Datasheet
This product is a 94.1 kDa Human LRRC8A membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LRRC8A
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 94.1 kDa
  • TMD
  • 4
  • Sequence
  • MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQD
    KMICLPCKWVTKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYD
    LDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTS
    SKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSST
    VSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKF
    RTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE
    SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKK
    YSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSEN
    KLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLVELEV
    LKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHI
    KFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLR
    LKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR
    CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNH
    IAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFL
    PADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV
    GELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFNTLPPEVKE
    RLWRADKEQA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • LRRC8A
  • Full Name
  • Leucine rich repeat containing 8 VRAC subunit A
  • Introduction
  • This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
  • Alternative Names
  • AGM5; LRRC8; SWELL1; volume-regulated anion channel subunit LRRC8A; leucine rich repeat containing 8 family member A; leucine-rich repeat-containing protein 8A; swelling protein 1; LRRC8A; Leucine rich repeat containing 8 VRAC subunit A

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