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Magic™ Membrane Protein Human MARCHF1 (Membrane associated ring-CH-type finger 1) Full Length (CAT#: MPC4037K) Made to Order

This product is a made-to-order Human MARCHF1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MARCHF1
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 2
  • Sequence
  • MLGWCEAIARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSS
    NISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCT
    GTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTS
    ERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTK
    LVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEK
    NFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • MARCHF1
  • Full Name
  • Membrane associated ring-CH-type finger 1
  • Introduction
  • MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment.
  • Alternative Names
  • MARCHF1; MARCH1; RNF171; MARCH-I; E3 ubiquitin-protein ligase MARCHF1; E3 ubiquitin-protein ligase MARCH1; RING finger protein 171; RING-type E3 ubiquitin transferase MARCH1; RING-type E3 ubiquitin transferase MARCHF1; membrane associated ring finger 1; membrane-associated RING finger protein 1; membrane-associated RING-CH protein I; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; Membrane associated ring-CH-type finger 1

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