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Magic™ Membrane Protein Human MARCHF4 (Membrane associated ring-CH-type finger 4) Expressed in vitro E.coli expression system, Full Length of Mature Protein (CAT#: MPX1774K)

Datasheet
This product is a Human MARCHF4 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MARCHF4
  • Protein Length
  • Full Length of Mature Protein
  • Protein Class
  • Transferase
  • TMD
  • 2
  • Sequence
  • WYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPQAPLPMHGDPQPPGLAANNTLPALGAGGWAGWRGPREVVGREPPPVPPPPPLPPSSVEDDWGGPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAAAILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYRIFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQGPAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVTTV

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • MARCHF4
  • Full Name
  • Membrane associated ring-CH-type finger 4
  • Introduction
  • MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.
  • Alternative Names
  • MARCHF4; MARCH4; RNF174; MARCH-IV; E3 ubiquitin-protein ligase MARCHF4; E3 ubiquitin-protein ligase MARCH4; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RING-type E3 ubiquitin transferase MARCHF4; membrane associated ring finger 4; membrane-associated RING finger protein 4; membrane-associated RING-CH protein IV; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; Membrane associated ring-CH-type finger 4

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