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Magic™ Membrane Protein Human MGAT1 (Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) Expressed in NS0 for Antibody Discovery, Partial (30-445aa) (CAT#: MPX0398K)

Datasheet
This product is a 48 kDa Human MGAT1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MGAT1
  • Protein Length
  • Partial (30-445aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 48 kDa
  • TMD
  • 1
  • Sequence
  • TRPAPGRPPSVSALDGDPASL
    TREVIRLAQDAEVELERQRGLLQQIGDALSSQRGRVPTAAPPAQPRVPVT
    PAPAVIPILVIACDRSTVRRCLDKLLHYRPSAELFPIIVSQDCGHEETAQ
    AIASYGSAVTHIRQPDLSSIAVPPDHRKFQGYYKIARHYRWALGQVFRQF
    RFPAAVVVEDDLEVAPDFFEYFRATYPLLKADPSLWCVSAWNDNGKEQMV
    DASRPELLYRTDFFPGLGWLLLAELWAELEPKWPKAFWDDWMRRPEQRQG
    RACIRPEISRTMTFGRKGVSHGQFFDQHLKFIKLNQQFVHFTQLDLSYLQ
    REAYDRDFLARVYGAPQLQVEKVRTNDRKELGEVRVQYTGRDSFKAFAKA
    LGVMDDLKSGVPRAGYRGIVTFQFRGRRVHLAPPLTWEGYDPSWN

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • MGAT1
  • Full Name
  • Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
  • Introduction
  • There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.
  • Alternative Names
  • MGAT1; GnTI; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; glcNAc-T I; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

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