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Magic™ Membrane Protein Human MGAT5 (Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) Expressed in NS0 for Antibody Discovery, Partial (189-741aa) (CAT#: MPX0769K)

Datasheet
This product is a 65 kDa Human MGAT5 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MGAT5
  • Protein Length
  • Partial (189-741aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 65 kDa
  • TMD
  • 1
  • Sequence
  • LSEVENWCPHLP
    WRAKNPYEEADHNSLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWI
    QAIKSLAEKQNLEKRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQ
    WSDLITSLYLLGHDIRISASLAELKEIMKKVVGNRSGCPTVGDRIVELIY
    IDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHANYAQSKGHKTP
    WGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHLNSSDIHHINEIKRQNQSL
    VYGKVDSFWKNKKIYLDIIHTYMEVHATVYGSSTKNIPSYVKNHGILSGR
    DLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKFNPPKSSKNTDF
    FIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEEVEDAVKAILNQKIE
    PYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQVKLAEPGQSCK
    QVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELAKDILVPSFDPKNK
    HCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALCKDCL

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris, NaCl and EDTA.

Target

  • Target Protein
  • MGAT5
  • Full Name
  • Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
  • Introduction
  • The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies.
  • Alternative Names
  • MGAT5; GNT-V; GNT-VA; MGAT5A; glcNAc-T V; N-acetylglucosaminyl-transferase V; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V; mannoside acetylglucosaminyltransferase 5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

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