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Magic™ Membrane Protein Human NOX4 (NADPH oxidase 4) Expressed in E.coli with 6xHis tag at the N-terminus for Antibody Discovery, Partial (210-424aa) (CAT#: MPX4299K)

This product is a 28.8 kDa Human NOX4 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NOX4
  • Protein Length
  • Partial (210-424aa)
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 28.8 kDa
  • TMD
  • 6
  • Sequence
  • GGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIRSNKPVTIISVMSHPSDVMEIRMVKENFKARPGQYITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYE

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • NOX4
  • Full Name
  • NADPH oxidase 4
  • Introduction
  • This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • KOX; KOX-1; RENOX; kidney oxidase-1; kidney superoxide-producing NADPH oxidase; renal NAD(P)H-oxidase; NOX4; NADPH oxidase 4

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