Close
Close

Magic™ Membrane Protein Human NPR2 (Natriuretic peptide receptor 2) Full Length (CAT#: MPC2241K) Made to Order

Datasheet
This product is a 117 kDa Human NPR2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NPR2
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 117 kDa
  • TMD
  • 1
  • Sequence
  • MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVA
    LAVEALGRALPVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPG
    CVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLG
    EFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQH
    QVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDY
    VFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
    PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNE
    TIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDL
    DSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDK
    TPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQ
    FGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAI
    KHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCP
    RGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNC
    VVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTT
    GMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRP
    SIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDN
    LLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGE
    TVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNF
    DVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRP
    HDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIH
    VSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NPR2
  • Full Name
  • Natriuretic peptide receptor 2
  • Introduction
  • This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
  • Alternative Names
  • NPR2; GCB; AMDM; ANPb; ECDM; GC-B; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B; atrial natriuretic peptide receptor 2; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor type B; guanylate cyclase 2B; guanylate cyclase B; guanylyl cyclase B; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); Natriuretic peptide receptor 2

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us