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Magic™ Membrane Protein Human NTRK2 (Neurotrophic receptor tyrosine kinase 2) Expressed in NS0 for Antibody Discovery, Partial (32-430aa) (CAT#: MPX0141K)

Datasheet
This product is a 71.7 kDa Human NTRK2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NTRK2
  • Protein Length
  • Partial (32-430aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 71.7 kDa
  • TMD
  • 1
  • Sequence
  • CPTSCKCSASRIWCSDPSP
    GIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVD
    SGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPF
    TCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSAN
    LAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSL
    RITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
    WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDN
    PTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDY
    GTAANDIGDTTNRSNEIPSTDVTDKTGREH

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • NTRK2
  • Full Name
  • Neurotrophic receptor tyrosine kinase 2
  • Introduction
  • This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • NTRK2; OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine kinase receptor type 2; tropomyosin-related kinase B; tyrosine kinase receptor B; Neurotrophic receptor tyrosine kinase 2

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