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Magic™ Membrane Protein Human PCDHB12 (Protocadherin beta 12) Full Length (CAT#: MPC4393K) Made to Order

Datasheet
This product is a made-to-order Human PCDHB12 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PCDHB12
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MENGGAGTLQIRQVLLFFVLLGMSQAGSETGNFLVMEELQSGSFVGNLAK
    TLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLLREMLDREELCGSNE
    PCVLYFQVLMKNPTQFLQIELQVRDINDHSPVFLEKEMLLEIPENSPVGA
    VFLLESAKDLDVGINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKAL
    DYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVK
    ILENSILGSLVVTVSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGD
    ITLTAPLDFEAIESYSIIIQATDGGGLFGKSTVRIQVMDVNDNAPEITVS
    SITSPIPENTPETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNY
    YTLETERPLDRESRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPA
    FTQTSYALFVRENNSPALHIGSISATDRDSGTNAQVNYSLLPSQDPHLPL
    ASLVSINADNGHLFALRSLDYEALQGFQFRVGATDHGSPALSSEALVRVL
    VLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVTKVVAVDGDSGQNA
    WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEP
    PRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSL
    FLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYH
    YEVCVTGGSRSNKFKFLKPIIPNFLPQSTGSEVEENPPFQNNLGF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • PCDHB12
  • Full Name
  • Protocadherin beta 12
  • Introduction
  • This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
  • Alternative Names
  • PCDHB12; PCDH-BETA12; protocadherin beta-12; PCDH-beta-12; Protocadherin beta 12

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