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Magic™ Membrane Protein Human PHEX (Phosphate regulating endopeptidase homolog X-linked) Expressed in Baculovirus/Insect expression system for Antibody Discovery, Partial (42-749aa) (CAT#: MPX0261K)

Datasheet
This product is a 83 kDa Human PHEX membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PHEX
  • Protein Length
  • Partial (42-749aa)
  • Protein Class
  • Protease
  • Molecular Weight
  • 83 kDa
  • TMD
  • 1
  • Sequence
  • QGLLSLQAK
    QEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPS
    YGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEK
    ADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSN
    SVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALY
    KFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKM
    NISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDL
    FRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLL
    PQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDML
    EKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEA
    DYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRF
    PAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLD
    PWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGL
    REAFRAYRKWINDRRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEA
    AREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • PHEX
  • Full Name
  • Phosphate regulating endopeptidase homolog X-linked
  • Introduction
  • The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • PHEX; HYP; PEX; XLH; HPDR; HYP1; LXHR; HPDR1; phosphate-regulating neutral endopeptidase PHEX; X-linked hypophosphatemia protein; metalloendopeptidase homolog PEX; phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets); vitamin D-resistant hypophosphatemic rickets protein; Phosphate regulating endopeptidase homolog X-linked

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