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Magic™ Membrane Protein Human PIGV (phosphatidylinositol glycan anchor biosynthesis class V) Full Length (CAT#: MPC4268K) Made to Order

Datasheet
This product is a made-to-order Human PIGV membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PIGV
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 10
  • Sequence
  • MWPQDPSRKEVLRFAVSCRILTLMLQALFNAIIPDHHAEAFSPPRLAPSG
    FVDQLVEGLLGGLSHWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLVGTE
    LLRPLRGLLSLRSCLLISVASLNFLFFMLAAVALHDLGCLVLHCPHQSFY
    AALLFCLSPANVFLAAGYSEALFALLTFSAMGQLERGRVWTSVLLFAFAT
    GVRSNGLVSVGFLMHSQCQGFFSSLTMLNPLRQLFKLMASLFLSVFTLGL
    PFALFQYYAYTQFCLPGSARPIPEPLVQLAVDKGYRIAEGNEPPWCFWDV
    PLIYSYIQDVYWNVGFLKYYELKQVPNFLLAAPVAILVAWATWTYVTTHP
    WLCLTLGLQRSKNNKTLEKPDLGFLSPQVFVYVVHAAVLLLFGGLCMHVQ
    VLTRFLGSSTPIMYWFPAHLLQDQEPLLRSLKTVPWKPLAEDSPPGQKVP
    RNPIMGLLYHWKTCSPVTRYILGYFLTYWLLGLLLHCNFLPWT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • PIGV
  • Full Name
  • phosphatidylinositol glycan anchor biosynthesis class V
  • Introduction
  • This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene.
  • Alternative Names
  • PIGV; PIG-V; HPMRS1; GPI-MT-II; GPI mannosyltransferase 2; GPI mannosyltransferase II; Ybr004c homolog; dol-P-Man dependent GPI mannosyltransferase; phosphatidylinositol glycan anchor biosynthesis class V

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