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Magic™ Membrane Protein Human PTPRA (Protein tyrosine phosphatase receptor type A) Full Length (CAT#: MPC1915K) Made to Order

Datasheet
This product is a 90.7 kDa Human PTPRA membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTPRA
  • Protein Length
  • Full length
  • Protein Class
  • Protein phosphatase
  • Molecular Weight
  • 90.7 kDa
  • TMD
  • 1
  • Sequence
  • MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTS
    NPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGIT
    ISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGNSDSKDRRDET
    PIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDV
    EPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPA
    CPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
    INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKC
    AQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLI
    TQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG
    TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
    HYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKM
    RTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
    DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD
    GLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV
    GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLE
    RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYAN
    FK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • PTPRA
  • Full Name
  • Protein tyrosine phosphatase receptor type A
  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
  • Alternative Names
  • PTPRA; LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); PTPLCA-related phosphatase; PTPase-alpha; protein tyrosine phosphatase, receptor type, alpha polypeptide; protein-tyrosine phosphatase alpha; tyrosine phosphatase alpha; Protein tyrosine phosphatase receptor type A

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