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Magic™ Membrane Protein Human SIGLEC10 (Sialic acid binding Ig like lectin 10) Expressed in NS0 for Antibody Discovery, Partial (17-546aa) (CAT#: MPX0645K)

Datasheet
This product is a 85 kDa Human SIGLEC10 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SIGLEC10
  • Protein Length
  • Partial (17-546aa)
  • Protein Class
  • Immunity
  • Molecular Weight
  • 85 kDa
  • TMD
  • 1
  • Sequence
  • MDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDW
    TGSTPAYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGN
    CSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYI
    PETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVL
    SFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNT
    PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP
    WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVM
    VSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLS
    PSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLG
    PSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAG
    PWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKGLIST

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SIGLEC10
  • Full Name
  • Sialic acid binding Ig like lectin 10
  • Introduction
  • SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).
  • Alternative Names
  • SIGLEC10; SLG2; PRO940; SIGLEC-10; sialic acid-binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; siglec-like gene 2; siglec-like protein 2; Sialic acid binding Ig like lectin 10

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