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Magic™ Membrane Protein Human SLC5A12 (Solute carrier family 5 member 12) Full Length (CAT#: MPC0891K) Made to Order

This product is a 67.6 kDa Human SLC5A12 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC5A12
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 67.6 kDa
  • TMD
  • 13
  • Sequence
  • MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSF
    GPVGLSLTASFMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFL
    PVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALAL
    NQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVL
    IQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWL
    GIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSH
    FKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVA
    SSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAAS
    VMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSF
    WVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWY
    SISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWS
    KKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPG
    YDPKDKSYNNMAFETTHF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC5A12
  • Full Name
  • Solute carrier family 5 member 12
  • Introduction
  • Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule.
  • Alternative Names
  • SMCT2; sodium-coupled monocarboxylate transporter 2; electroneutral sodium monocarboxylate cotransporter; low-affinity sodium-lactate cotransporter; sodium-iodide related cotransporter; solute carrier family 5 (sodium/glucose cotransporter), member 12; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12; SLC5A12; Solute carrier family 5 member 12

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