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Magic™ Membrane Protein Human SMPD4 (Sphingomyelin phosphodiesterase 4) Expressed in Wheat Germ Cell-free Expression System, Full length (CAT#: MPX4714K)

This product is a Human SMPD4 membrane protein expressed in wheat germ cell-free expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SMPD4
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 116.5 kDa
  • TMD
  • 1
  • Sequence
  • MAFPHLQQPSFLLASLKADSINKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCL
    QGRVNPVEYSIVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP
    TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGSVPPPLSSSPGGT
    SPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSETLLQVFVEMWLHHYSLEMYQKMQ
    SPHAKESFTPTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFLQH
    CFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMYTKLFVGFLNR
    ALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQHRLFTAPTFTGSFLSPWPPAVTD
    ASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLITQAKHTAKSISDQCAESPAGHSFLSWLGFSSMD
    TNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDG
    LILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRY
    HLTEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCTLLLTLGYVLYA
    SAMTLLTERGKLHQP

Product Description

  • Expression Systems
  • Wheat Germ Cell-free Expression System
  • Protein Format
  • Soluble
  • Buffer
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0

Target

  • Target Protein
  • SMPD4
  • Full Name
  • Sphingomyelin phosphodiesterase 4
  • Introduction
  • The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
  • Alternative Names
  • SMPD4; SKNY; NET13; NEDMABA; NEDMEBA; NSMASE3; NSMASE-3; neutral sphingomyelinase 3; neutral sphingomyelinase III; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3); Sphingomyelin phosphodiesterase 4

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