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Magic™ Membrane Protein Human SPPL2A (Signal peptide peptidase like 2A) Full Length (CAT#: MPC1128K) Made to Order

This product is a 58.1 kDa Human SPPL2A membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPPL2A
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • Molecular Weight
  • 58.1 kDa
  • TMD
  • 9
  • Sequence
  • MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWT
    ALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEK
    ARIAQKGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQ
    TLGDNITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKA
    VTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIA
    IFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVA
    VVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLY
    DVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSV
    CLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMIL
    TFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDH
    LDCATNEENPVISGEQIVQQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SPPL2A
  • Full Name
  • Signal peptide peptidase like 2A
  • Introduction
  • This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.
  • Alternative Names
  • SPPL2A; IMP3; PSL2; signal peptide peptidase-like 2A; IMP-3; SPP-like 2A; intramembrane cleaving protease; intramembrane protease 3; presenilin-like protein 2; PSEC0147; Signal peptide peptidase like 2A

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