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Magic™ Membrane Protein Human SRD5A3 (Steroid 5 alpha-reductase 3) Expressed in vitro E.coli expression system, Full Length (CAT#: MPX2713K)

Datasheet
This product is a Human SRD5A3 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SRD5A3
  • Protein Length
  • Full Length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 6
  • Sequence
  • MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEPSRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFLF

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • SRD5A3
  • Full Name
  • Steroid 5 alpha-reductase 3
  • Introduction
  • The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq.
  • Alternative Names
  • SRD5A3; CDG1P; CDG1Q; KRIZI; SRD5A2L; SRD5A2L1; polyprenol reductase; 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)); 3-oxo-5-alpha-steroid 4-dehydrogenase 3; S5AR 3; SR type 3; probable polyprenol reductase; Steroid 5 alpha-reductase 3

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