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Magic™ Membrane Protein Human STEAP2 (STEAP2 metalloreductase) Expressed in vitro E.coli expression system, Full Length (CAT#: MPX0944K)

Datasheet
This product is a Human STEAP2 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • STEAP2
  • Protein Length
  • Full Length
  • Protein Class
  • Oxidoreductase
  • Molecular Weight
  • 74.6kDa
  • TMD
  • 6
  • Sequence
  • MESISMMGSPKSLSETFLPNGINGIKDARKVTVGVIGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFFPHVVDVTHHEDALTKTNIIFVAIHREHYTSLWDLRHLLVGKILIDVSNNMRINQYPESNAEYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVVAISLATFFFLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAGLLAAAYQLYYGTKYRRFPPWLETWLQCRKQLGLLSFFFAMVHVAYSLCLPMRRSERYLFLNMAYQQVHANIENSWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWREFSFIQSTLGYVALLISTFHVLIYGWKRAFEEEYYRFYTPPNFVLALVLPSIVILGKIILFLPCISRKLKRIKKGWEKSQFLEEGMGGTIPHVSPERVTVM

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 10xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • STEAP2
  • Full Name
  • STEAP2 metalloreductase
  • Introduction
  • This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Alternative Names
  • STEAP2; STMP; IPCA1; PUMPCn; STAMP1; PCANAP1; metalloreductase STEAP2; STEAP family member 2, metalloreductase; SixTransMembrane Protein of Prostate 1; prostate cancer-associated protein 1; protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; six transmembrane epithelial antigen of the prostate 2; six-transmembrane epithelial antigen of prostate 2; STEAP2 metalloreductase

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