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Magic™ Membrane Protein Human SUN2 (Sad1 and UNC84 domain containing 2) Full Length (CAT#: MPC2171K) Made to Order

This product is a 80.3 kDa Human SUN2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SUN2
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 80.3 kDa
  • TMD
  • 1
  • Sequence
  • MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNM
    KRLSPAPQLGPSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLR
    VRRRRGTGGSESSRASGLVGRKATEDFLGSSSGYSSEDDYVGYSDVDQQS
    SSSRLRSAVSRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDV
    FVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWA
    AKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK
    EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRE
    TAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQ
    ESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVR
    DDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQ
    GKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYA
    LESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN
    CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFG
    FDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGH
    PEYTCIYRFRVHGEPAH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SUN2
  • Full Name
  • Sad1 and UNC84 domain containing 2
  • Introduction
  • SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity.
  • Alternative Names
  • SUN2; UNC84B; rab5IP; SUN domain-containing protein 2; Sad1 unc-84 domain protein 2; nuclear envelope protein; protein unc-84 homolog B; rab5-interacting protein; sad1/unc-84 protein-like 2; unc-84 homolog B; Sad1 and UNC84 domain containing 2

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