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Magic™ Membrane Protein Human SURF1 (SURF1 cytochrome c oxidase assembly factor) Expressed in E.coli for Antibody Discovery, Partial (80-273aa) (CAT#: MPX0165K)

Datasheet
This product is a 28 kDa Human SURF1 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SURF1
  • Protein Length
  • Partial (80-273aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 28 kDa
  • TMD
  • 2
  • Sequence
  • MGSSHHHHHHSSGLVPRGSHMQVQRRKWKLNLIAELESRVLAEPVPLPADPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQIEGEVDLIGMVRLTETRQPFVPENNPERNHWHYRDLEAMARITGAEPIFIDANFQSTVPGGPIGGQTRVTLRNEHLQ

Product Description

  • Expression Systems
  • E.coli
  • Protein Format
  • Soluble
  • Purity
  • > 95 % SDS-PAGE.
  • Buffer
  • pH: 8.00, Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

Target

  • Target Protein
  • SURF1
  • Full Name
  • SURF1 cytochrome c oxidase assembly factor
  • Introduction
  • This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
  • Alternative Names
  • SURF1; SHY1; CMT4K; MC4DN1; surfeit locus protein 1; SURF1 cytochrome c oxidase assembly factor

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