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Magic™ Membrane Protein Human SV2B (Synaptic vesicle glycoprotein 2B) Full Length (CAT#: MPC1079K) Made to Order

This product is a 77.4 kDa Human SV2B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SV2B
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 77.4 kDa
  • TMD
  • 12
  • Sequence
  • MDDYKYQDNYGGYAPSDGYYRGNESNPEEDAQSDVTEGHDEEDEIYEGEY
    QGIPHPDDVKAKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMD
    ECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGML
    GMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGA
    FLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYA
    SAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPES
    PRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFI
    EIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAM
    AFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQ
    HGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFY
    NTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVL
    PGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFC
    GTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVG
    ITKVVPILLAAASLVGGGLIALRLPETREQVLM

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SV2B
  • Full Name
  • Synaptic vesicle glycoprotein 2B
  • Introduction
  • This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients.
  • Alternative Names
  • SV2B; HsT19680; synaptic vesicle protein 2B homolog; KIAA0735; Synaptic vesicle glycoprotein 2B

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