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Magic™ Membrane Protein Human TAS2R38 (Taste 2 receptor member 38) Full Length (CAT#: MPC0264K) Made to Order

Datasheet
This product is a 37.8 kDa Human TAS2R38 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TAS2R38
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 37.8 kDa
  • TMD
  • 7
  • Sequence
  • MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQAL
    SNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWM
    IANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSRKISQMLLGIILC
    SCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFCYL
    WSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLEAHIKALKSLV
    SFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG
    NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TAS2R38
  • Full Name
  • Taste 2 receptor member 38
  • Introduction
  • This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).
  • Alternative Names
  • PTC; T2R38; T2R61; THIOT; taste receptor type 2 member 38; PTC bitter taste receptor; taste receptor type 2 member 61; taste receptor, type 2, member 38; TAS2R38; Taste 2 receptor member 38

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