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Magic™ Membrane Protein Human THBD (Thrombomodulin) Expressed in E.coli with 6xHis and KSI tag at the N-terminus for Antibody Discovery, Partial (200-500aa) (CAT#: MPX4100K)

This product is a 47.0 kDa Human THBD membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • THBD
  • Protein Length
  • Partial (200-500aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 47.0 kDa
  • TMD
  • 1
  • Sequence
  • RGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGGDSGSGEPPPSPT

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis and KSI tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • THBD
  • Full Name
  • Thrombomodulin
  • Introduction
  • The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
  • Alternative Names
  • TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12; CD141 antigen; fetomodulin

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