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Magic™ Membrane Protein Human TLR8 (Toll like receptor 8) Full Length (CAT#: MPC2639K) Made to Order

Datasheet
This product is a made-to-order Human TLR8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TLR8
  • Protein Length
  • Full length
  • Protein Class
  • Receptor; Immunity
  • TMD
  • 1
  • Sequence
  • MENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECS
    NRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNV
    QHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTE
    LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETL
    TNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTL
    LDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLR
    KINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIK
    GSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTIN
    LGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRH
    IRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ
    FENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASAL
    TELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLT
    DKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNR
    LKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL
    LFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKT
    INKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVD
    VICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHH
    LFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINE
    LRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKY
    AKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSS
    ILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • TLR8
  • Full Name
  • Toll like receptor 8
  • Introduction
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
  • Alternative Names
  • TLR8; CD288; toll-like receptor 8; Toll like receptor 8

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