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Magic™ Membrane Protein Human TMUB1 (Transmembrane and ubiquitin like domain containing 1) (CAT#: MP0096J)

Datasheet
This product is a 26.1 kDa Human TMUB1 membrane protein expressed in HEK293T. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMUB1
  • Protein Length
  • Full-length
  • Protein Class
  • Druggable Genome, Transmembrane
  • Molecular Weight
  • 26.1 kDa
  • TMD
  • 3
  • Sequence
  • MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGGDPLPQPSGTPTPSQPSAAMAATDSMRGEAPGAE
    TPSLRHRGQAAQPEPSTGFTATPPAPDSPQEPLVLRLKFLNDSEQVARAWPHDTIGSLKRTQFPGREQQV
    RLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPNPPCPPGSEPGPSGLEIGSLLLPLLLLLLLLL
    WYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMYRP

Product Description

  • Expression Systems
  • HEK293T
  • Tag
  • C-Myc/DDK
  • Purification
  • Anti-DDK affinity column followed by conventional chromatography steps
  • Purity
  • > 80% as determined by SDS-PAGE and Coomassie blue staining
  • Buffer
  • 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Target

  • Target Protein
  • TMUB1
  • Full Name
  • Transmembrane and ubiquitin like domain containing 1
  • Introduction
  • Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration.
  • Alternative Names
  • DULP; HOPS; SB144; C7orf21; dendritic cell-derived ubiquitin-like protein; hepatocyte odd protein shuttling protein; ubiquitin-like protein DULP; ubiquitin-like protein SB144

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