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Magic™ Membrane Protein Human TREM1 (Triggering receptor expressed on myeloid cells 1) Expressed in NS0 for Antibody Discovery, Partial (21-200aa) (CAT#: MPX0727K)

Datasheet
This product is a 47 kDa Human TREM1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TREM1
  • Protein Length
  • Partial (21-200aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 47 kDa
  • TMD
  • 1
  • Sequence
  • ATKLTEEKYELKEGQTLDVKCDYTLEKFAS
    SQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRM
    VNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSGTPGSNENSTQN
    VYKIPPTTTKALCPLYTSPRTVTQAPPKSTADVSTPDSEINLTNVTDIIR

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • TREM1
  • Full Name
  • Triggering receptor expressed on myeloid cells 1
  • Introduction
  • This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
  • Alternative Names
  • TREM1; CD354; TREM-1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells 1

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