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Magic™ Membrane Protein Human TUSC3 (Tumor suppressor candidate 3) Expressed in vitro E.coli expression system, Full Length of Mature Protein (CAT#: MPX2414K)

Datasheet
This product is a Human TUSC3 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TUSC3
  • Protein Length
  • Full Length of Mature Protein
  • Protein Class
  • Transport
  • TMD
  • 4
  • Sequence
  • QKKKENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSDLDFE

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • TUSC3
  • Full Name
  • Tumor suppressor candidate 3
  • Introduction
  • This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform.
  • Alternative Names
  • TUSC3; M33; N33; MRT7; MRT22; MagT2; OST3A; D8S1992; SLC58A2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; magnesium uptake/transporter TUSC3; mental retardation, non-syndromic, autosomal recessive, 22; oligosaccharyl transferase subunit TUSC3; oligosaccharyltransferase 3 homolog A; putative prostate cancer tumor suppressor; Tumor suppressor candidate 3

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