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Magic™ Membrane Protein Human VSIG4 (V-set and immunoglobulin domain containing 4) Expressed in NS0 for Antibody Discovery, Partial (20-283aa) (CAT#: MPX0627K)

Datasheet
This product is a 30 kDa Human VSIG4 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • VSIG4
  • Protein Length
  • Partial (20-283aa)
  • Protein Class
  • Immunity
  • Molecular Weight
  • 30 kDa
  • TMD
  • 1
  • Sequence
  • RPILEVPESVTGPWKGDVNLPCTYDPLQGYT
    QVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQL
    STLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSG
    YGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKP
    AVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYP
    LKATSTVKQSWDWTTDMDGYLGETSAGPGKSLP

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • VSIG4
  • Full Name
  • V-set and immunoglobulin domain containing 4
  • Introduction
  • This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • VSIG4; CRIg; Z39IG; Ig superfamily protein; complement receptor of the immunoglobulin superfamily; protein Z39Ig; V-set and immunoglobulin domain containing 4

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