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Magic™ Membrane Protein SARS2 N Mutation (R203K, G204R) (Nucleocapsid phosphoprotein) Expressed in E.coli for Antibody Discovery, Partial (2-419aa) (CAT#: MPX0352K)

Datasheet
This product is a 46.5 kDa SARS2 N Mutation (R203K, G204R) membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • SARS2
  • Target Protein
  • N Mutation (R203K, G204R)
  • Protein Length
  • Partial (2-419aa)
  • Protein Class
  • Host-virus interaction
  • Molecular Weight
  • 46.5 kDa
  • Sequence
  • SDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTA
    SWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGK
    MKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRN
    PANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPG
    SSKRTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKS
    AAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKH
    WPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQV
    ILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADL
    DDFSKQLQQSMSSADSTQA

Product Description

  • Expression Systems
  • E.coli
  • Purity
  • > 85 % as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from sterile 50 mM PB, 500 mM NaCl, pH 7.0.

Target

  • Target Protein
  • N Mutation (R203K, G204R)
  • Full Name
  • Nucleocapsid phosphoprotein
  • Introduction
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the RNA into virus particles. The N protein has been suggested as an antiviral drug target.
  • Alternative Names
  • N Mutation (R203K, G204R); ORF9; structural protein; Nucleocapsid phosphoprotein

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