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NativeExtract™ Human ACKR3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX399)

Datasheet
This product is recombinant Human ACKR3 protein in native nanodisc form. The synthetic compound we developed can solubilize the ACKR3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACKR3
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACKR3
  • Full Name
  • Atypical chemokine receptor 3
  • Introduction
  • This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
  • Alternative Names
  • ACKR3; RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159; C-X-C chemokine receptor type 7; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1; Atypical chemokine receptor 3

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