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NativeExtract™ Human ACKR4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX336)

Datasheet
This product is recombinant Human ACKR4 protein in native nanodisc form. The synthetic compound we developed can solubilize the ACKR4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ACKR4
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.9kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ACKR4
  • Full Name
  • Atypical chemokine receptor 4
  • Introduction
  • The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.
  • Alternative Names
  • ACKR4; PPR1; CCBP2; CCR10; CCR11; CCRL1; VSHK1; CCR-11; CKR-11; CCX CKR; CCX-CKR; CC-CKR-11; C-C CKR-11; C-C chemokine receptor type 11; CC chemokine receptor-like 1; chemocentryx chemokine receptor; chemokine (C-C motif) receptor-like 1; chemokine, cc motif, receptor-like protein 1; orphan seven-transmembrane receptor, chemokine related; Atypical chemokine receptor 4

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