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NativeExtract™ Human ADGRE3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX317)

Datasheet
This product is recombinant Human ADGRE3 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADGRE3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRE3
  • Protein Length
  • Full length
  • Molecular Weight
  • 72.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADGRE3
  • Full Name
  • Adhesion G protein-coupled receptor E3
  • Introduction
  • This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • EMR3; EGF-like module receptor 3; EGF-like module-containing mucin-like hormone receptor-like 3; egf-like module containing, mucin-like, hormone receptor-like 3; egf-like module-containing mucin-like receptor 3; ADGRE3; Adhesion G protein-coupled receptor E3

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