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NativeExtract™ Human ADRA1A Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX330)

Datasheet
This product is recombinant Human ADRA1A protein in native nanodisc form. The synthetic compound we developed can solubilize the ADRA1A protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADRA1A
  • Protein Length
  • Full length
  • Molecular Weight
  • 51.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADRA1A
  • Full Name
  • Adrenoceptor alpha 1A
  • Introduction
  • Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
  • Alternative Names
  • ADRA1C; ADRA1L1; ALPHA1AAR; G protein coupled receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; ADRA1A; Adrenoceptor alpha 1A

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