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NativeExtract™ Human ADRB3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX323)

Datasheet
This product is recombinant Human ADRB3 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADRB3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADRB3
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADRB3
  • Full Name
  • Adrenoceptor beta 3
  • Introduction
  • The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.
  • Alternative Names
  • BETA3AR; adrenergic, beta-3-, receptor; beta-3 adrenoceptor; beta-3 adrenoreceptor; ADRB3; Adrenoceptor beta 3

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