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NativeExtract™ Human BDKRB1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX300)

Datasheet
This product is recombinant Human BDKRB1 protein in native nanodisc form. The synthetic compound we developed can solubilize the BDKRB1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BDKRB1
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • BDKRB1
  • Full Name
  • Bradykinin receptor B1
  • Introduction
  • Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
  • Alternative Names
  • B1R; BKR1; B1BKR; BKB1R; BRADYB1; BK-1 receptor; bradykinin B1 receptor; bradykinin receptor 1; BDKRB1; Bradykinin receptor B1

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