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NativeExtract™ Human CCKAR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX295)

Datasheet
This product is recombinant Human CCKAR protein in native nanodisc form. The synthetic compound we developed can solubilize the CCKAR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCKAR
  • Protein Length
  • Full length
  • Molecular Weight
  • 47.8kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CCKAR
  • Full Name
  • Cholecystokinin A receptor
  • Introduction
  • This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
  • Alternative Names
  • CCK-A; CCK1R; CCKRA; CCK1-R; CCK-A receptor; CCK-AR; cholecystokinin type-A receptor; cholecystokinin-1 receptor; cholecystokinin receptor type A; CCKAR; Cholecystokinin A receptor

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