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NativeExtract™ Human CHRM1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX335)

Datasheet
This product is recombinant Human CHRM1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CHRM1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CHRM1
  • Protein Length
  • Full length
  • Molecular Weight
  • 51.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CHRM1
  • Full Name
  • Cholinergic receptor muscarinic 1
  • Introduction
  • The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
  • Alternative Names
  • M1; HM1; M1R; muscarinic acetylcholine receptor M1; acetylcholine receptor, muscarinic 1; CHRM1; Cholinergic receptor muscarinic 1

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