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NativeExtract™ Human CHRM3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX334)

Datasheet
This product is recombinant Human CHRM3 protein in native nanodisc form. The synthetic compound we developed can solubilize the CHRM3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CHRM3
  • Protein Length
  • Full length
  • Molecular Weight
  • 66.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CHRM3
  • Full Name
  • Cholinergic receptor muscarinic 3
  • Introduction
  • The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
  • Alternative Names
  • HM3; PBS; EGBRS; muscarinic acetylcholine receptor M3; acetylcholine receptor, muscarinic 3; m3 muscarinic receptor; CHRM3; Cholinergic receptor muscarinic 3

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