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NativeExtract™ Human CXCR5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX444)

This product is recombinant Human CXCR5 protein in native nanodisc form. The synthetic compound we developed can solubilize the CXCR5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CXCR5
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.0 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CXCR5
  • Full Name
  • C-X-C motif chemokine receptor 5
  • Introduction
  • This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Alternative Names
  • BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CXC-R5; CXCR-5; MDR-15; chemokine (C-X-C motif) receptor 5; monocyte-derived receptor 15; CXCR5; C-X-C motif chemokine receptor 5

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