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NativeExtract™ Human EDNRA Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX279)

Datasheet
This product is recombinant Human EDNRA protein in native nanodisc form. The synthetic compound we developed can solubilize the EDNRA protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EDNRA
  • Protein Length
  • Full length
  • Molecular Weight
  • 48.7kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • EDNRA
  • Full Name
  • Endothelin receptor type A
  • Introduction
  • This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ETA; ET-A; ETAR; ETRA; MFDA; ETA-R; hET-AR; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor; EDNRA; Endothelin receptor type A

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