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NativeExtract™ Human FZD2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX270)

Datasheet
This product is recombinant Human FZD2 protein in native nanodisc form. The synthetic compound we developed can solubilize the FZD2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FZD2
  • Protein Length
  • Full length
  • Molecular Weight
  • 63.6kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • FZD2
  • Full Name
  • Frizzled class receptor 2
  • Introduction
  • This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
  • Alternative Names
  • Fz2; fz-2; fzE2; hFz2; OMOD2; frizzled-2; frizzled 2, seven transmembrane spanning receptor; frizzled family receptor 2; frizzled homolog 2; FZD2; Frizzled class receptor 2

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