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NativeExtract™ Human GPR150 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX243)

Datasheet
This product is recombinant Human GPR150 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR150 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR150
  • Protein Length
  • Full length
  • Molecular Weight
  • 46.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR150
  • Full Name
  • G protein-coupled receptor 150
  • Introduction
  • This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes.
  • Alternative Names
  • PGR11; probable G-protein coupled receptor 150; seven transmembrane helix receptor; GPR150; G protein-coupled receptor 150

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